TY - JOUR T1 - Effects of singular and combined administration of Pediococcus acidilactici and Agaricus bisporus on some blood indices and non-specific immune parameters of common carp (Cyprinus carpio) TT - تاثیر استفاده مجزا و تلفیقی پروبیوتیک Pediococcus acidilactici و پودر قارچ Agaricus bisporus بر برخی شاخص‌های خونی و شاخص‌های ایمنی غیراختصاصی سرم در بچه ماهی کپور معمولی پرورشی (Cyprinus carpio) JF - ISFJ JO - ISFJ VL - 26 IS - 5 UR - http://isfj.ir/article-1-1833-en.html Y1 - 2018 SP - 61 EP - 70 KW - Blood indices KW - Non-specific immunity KW - Common carp N2 - This study was conducted to investigate the effects of Pediococcus acidilactici and Agaricus bisporus administration on some blood and non-specific immune parameters of common carp (Cyprinus carpio). The total number of 180 fish with average weight of 19.06±0.69 g was adapted to laboratory conditions for 2 weeks. Afterwards, they were divided into 12 fiberglass tanks with the density of 15 fish in a tank. The study was performed in a complete randomize design for 2 months using 4 dietary treatments including the commercial diet (control group), commercial diet supplemented with P. acidilactici (0/9×107 CFU/g), commercial diet supplemented with mushroom powder (10 g/kg), and commercial diet supplemented with the combination of P. acidilactici (0/9×107 CFU/g) and mushroom powder (10 g/kg). At the end of the study, the results indicated that there was no significant difference in the number of red blood cells (RBC) among various groups. The highest levels of hemoglobin )8/15±0/37)(g/dL), MCV, 223/63±23/77(fL), MCH, 56/21±5/31(pg) and the lowest amount of white blood cell count, 9/73±1/00 (×103 cell/ml) were observed in the synbiotic group (P<0.05). Furthermore, hematocrit (32/43±1/69%) and MCHC (25/17±1/06 %) showed a slight increase in the synbiotic treatment compared to the control group (P>0.05). Significant differences in the total immunoglobulin, lysozyme activity and ACH50 were not found among various experimental groups (P<0.05). In conclusion, the commercial diet supplemented with the combination of the probiotic (0/9×107 CFU/g) and prebiotic (10 g/kg) improved some blood parameters in common carp. M3 ER -