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This study was performed to measure the amounts of heavy metals lead, nickel, zinc, iron and copper in tissue of Liza klunzingeri fishes of islands (Qeshm, Hengam and Hormoz) in Hormozgan province during summer to winter 2019. After biometry muscle tissues of 180 samples should be omitted were isolated and frizzed. Then the samples were prepared by acid digestion method and the amount of heavy metals was measured by using a flame atomic absorption device (700Contr AA model). The results should be omitted showed that the highest mean concentrations of studied metals (lead: 0.082 ± 0.009, nickel: 0.646± 0.07, zinc: 31.97±1.33 and copper: 0.881 ± 0.03 micrograms per gram)  were in Qeshm Island and the highest mean heavy metal concentration of iron (19.30± 0.75 Micrograms per gram) was in Hormoz Island and the lowest mean concentration of heavy metals (lead: 0.036 ±0.007, nickel: 0.348 ± 0.05, zinc: 15.13 ±1.06, copper: 0.657± 0.04 and iron: 12.13 ±0.4 Micrograms per gram)  were observed in Hengam Island. The concentrations of metals in the analyzed samples were lower than the international standards of the FAO, the WHO, the FDA, the Australian National Institutes of Health (NHMRC) and the UK Food and Drug Administration (UKMAFF) and statistically significant differences were observed. Also, the level of potential risk and risk index for non-cancerous diseases in adults and children in the muscle tissue of barley fish were less than 1. Therefore, according to the results of this study, the current use of this species of fish for human consumption will not pose a problem from the perspective of health and public health.