Sargassum ilicifolium were collected from 18 stations of Sistan and Baluchistan coastal waters, washed out, dried and powdered then transferred to laboratory for biochemical analyzing of total protein (% DW) using Kejeldal method, amino acids  using HPLC device, Crude fat (%DW) using Soxoleh method, Fatty acids with GC  device after determination of FAMES, carbohydrate (%DW) with phenol sulfuric acid method, vitamins  with HPLC device, Ash content using burning in Avon, minerals with flame photometry and astaxanthin with spectrophotometry and statistical analysis using SPSS, Ver. 14. Results showed that Sargassum collected from Tis beach  near the Chabahar bay in dried  form with  9.18±1.15% protein (p<0.05), 2.18±0.15% crude fat (p>0.05), 1.2% EF(p>0.05), 33.11±2.03% carbohydrate(p<0.05), 230.14±11.83 Kcal 100^-1  energy(p<0.05), 11.11±1.03% minerals(p<0.05), 115.51±10.87 mg vitamin complex in 100 g seaweed DW (p<0.05) and 104.11±1.00 µg Astaxanthin in 100 g seaweed DW(p<0.05) had higher nutritional values comparing the samples collected from other areas. Essential fatty acids of sargassum  collected from Tis had higher amount (p<0.05) compared to the others but amino acid profiles had not (p>0.05)except lysine(p<0.05).