Today, the use of herbal drugs has been developed in animal husbandry. Rainbow trout is also known as an important fish for breeding. The purpose of this study was to determine the effects of oral consumption of Aloe Vera gel on growth performance and some blood parameters of rainbow trout. The number of 90 apparently healthy rainbow trout on a biological condition with an approximate weight of 107 ± 3.5g was divided into two groups: control (basal diet) and treatment (basal diet + 0.5% Aloe vera gel) with 3 replications and in terms of fish appetizers were fed to the extent. At the end of the 2-month period, the food conversion ratio and blood sample (Total protein, Albumin, AST, ALT, White and Red blood cells, Hematocrit, Glucose, Cholesterol, Triglycerides and Uric acid) were measured. The results showed that the food conversion ratio was lower than the control group (p<0.05). Blood biochemical analysis showed no significant changes in Total protein, Albumin, AST, ALT and Uric acid between control and treatment group (p> 0.05), but significant reduction was observed in Glucose, Cholesterol and Triglyceride (p<0.05). According to the results, oral consumption of Aloe vera gel can be effective in improving the nutritional performance and reduce the physiological sugar and lipids of blood, and it is recommended during the period of breeding mentioned fish.